Lab outing!

- 5/10/2024

 

 

Katie won 2024 Saul Winegrad Award for Outstanding Dissertation!

The Award was established in 1995 in honor of the founding Director of Biomedical Graduate Study at Penn, Saul Winegrad, MD, Emeritus Professor of Physiology. The award was created to recognize a dissertation of outstanding quality which makes a significant contribution to biomedical science.

- 4/25/2024

 

 

Congratulations to our new Dr. Martinez!

- 4/11/2024

 

 

Congratulations to our new Dr. Kixmoeller!

- 3/22/2024

 

 

Congratulations to our new Dr. Creekmore!

- 3/21/2024

 

 

Our new paper from the collaborative project with the Soldati lab is featured in the Editor’s Highlights of Nature Communications!

- 3/20/2024

 

 

Katie won John G. Clark Prize!

2024 Medical Student Research Paper Prize Competition

Title: Visualization of human kinetochores by cryo-electron tomography

3/15/2024

 

 

Ben won Neurosurgery Research Prize!

2024 Medical Student Research Paper Prize Competition

Title: Ultrastructure of human brain tissue vitrified directly from autopsy revealed by cryo-electron tomography with cryo-plasma focused ion beam milling

3/15/2024

 

 
Yi-Wei Chang lab at the BMB retreat

The lab at the 2023 Biochemistry and Molecular Biophysics retreat!

 

 

Ruchao received the Mildred Cohn Distinguished Postdoctoral Award!

- 9/1/2023

 

 

Matt received the Blavatnik Family Fellowship in Biomedical Research!

- 9/1/2023

 

 

Our new work led by Matt and Shrawan using cryo-ET to investigate actin filaments in apicomplexan parasites has allowed us to learn where do these filaments originate at the cell tip and how they could be managed down the cell body to power motility! (link)

- 8/9/2023

 

 

Yi-Wei is appointed Associate Director of the new Institute of Structural Biology at Penn

Led by Prof. Vera Moiseenkova-Bell, the new Institute will integrate and expand the extensive structural biology resources and expertise across the campus to maximize their impact in research, education, and medicine.

- 7/1/2023

 

 
 

 

(VIDEO) Structural Biology at Penn - Bringing the language of life into focus

 

 

Leon won NIH F31 fellowship!!

- 3/30/2023

 

 

Leon’s work using single particle cryo-ET to visualize dynamic changes in DNA organization of transcription pre-initiation complexes on a divergent promoter is published!! (link)

- 2/1/2023

 

 

Matt won the 2022 P. Leslie Dutton Award for Outstanding Publication by a BMB student!

and delivered a wonderful award presentation at the BMB annual retreat!

- 2022/12/2

 

 

Matt giving an amazing talk at the Molecular Parasitology Meeting 2022!

- 2022/09/22

 

 

Ben won NIH F30 dual-degree fellowship!!

- 8/19/2022

 

 

Liam is joining Harvard for his PhD!

Congratulations to our long-term, super-productive undergraduate student Liam Theveny! We can’t wait to see all the amazing things Liam will be doing at Harvard!

- Summer 2022

 

 

Billy is going to Caltech for his PhD!

Congratulations to our inaugural lab member William (Billy) Chen! After spending the entire undergraduate time in our lab and made countless contributions, Billy is going to Caltech and blow everyone there away!

- Summer 2022

 

 

Matt showcasing cryo-EM sample preparation for visiting high school students

- 07/20/2022

 

 

Matt’s work resolving the in situ structure and activities of the rhoptry secretory apparatus in the malaria parasite Plasmodium falciparum is published! (link)

- 7/11/2022

 

 

Lab BBQ party at Yi-Wei’s

- 4/24/2022

 

 

We are on the journal cover!! (link to the issue)

- 5/2022

 

 

Yi-Wei joins the EMBO Journal Catalysts Program, aiming to stimulate innovations among different scientific fields and to advance scientific publishing workflows, policies and inclusiveness. (link)

- 3/1/2022

 

 

Matt won the inaugural Martin and Pamela Winter Infectious Disease Fellowship!!

- 02/24/2022

 

 

Liam and Shrawan’s great review on how the latest cryo-ET technologies are advancing in situ structural parasitology research!

- 2/8/2022

 

 

Secret Santa 2021

- 12/16/2021

 

 

Yi-Wei led the team to win the Beckman Foundation 2022 FIB-Milling Sample Preparation for Cellular CryoET Award! (link)

This will enable the acquisition of a cutting-edge cryo-focused ion beam instrument for cryo-ET sample preparation and beyond!

- 12/6/2021

 

 

Shrawan won the annual

S. Walter Englander Award for Postdoctoral Research at Penn!!

- 10/29/2021

 

 
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Shrawan and Amandine presenting their beautiful works at the Molecular Parasitology Meeting XXXII!

- 10/5/2021

 

 

In-person lab meeting after 1.5yr!

- 9/20/2021

 

 

Amazing work led by Shrawan providing new structural and mechanistic insights into the apicomplexan rhoptry secretion system! (link)

- 8/17/2021

 

 
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Ben is appointed to the Structural Biology & Molecular Biophysics T32 training program!

- 7/5/2021

 

 
 
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Ben’s reviews are on the journal cover! (link)

- 6/16/2021

 

 
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Celebrating for Ben, Katie, Matt, and Leon passed their PhD candidacy exams together in the span of 1 week!

- 5/11/2021

 

 

Ben’s new back-to-back review articles on how cryo-EM has provided new insights into proteostasis factors and aggregates in neurodegenerative diseases!

- 4/17/2021 & 5/10/2021

 

 
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Katie won NIH F30 dual-degree fellowship!!

- 2/17/2021

 

 

A fantastic collaboration with the Lebrun, Turkewitz, and Striepen labs!

- 1/25/2021

 

 
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Hiking, 2020 style

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@ Ridley Park

- 9/19/2020

 

 

Virtual lab meeting

- 5/2020

 

Yi-Wei named Packard Fellow!
— 10/15/2019
 

 

Yi-Wei and team won the ASPIRE Award from the Mark Foundation for Cancer Research to combine cutting-edge computational analyses with in situ cryo-ET to study cancer biology! (link)

 

 
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YEAR 1

- 8/6/2019

 

 
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First

cryo-ET session

- 7/24/2019

 

 
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Spring 2019

- 6/4/2019

 

 
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First lab meeting

- 6/4/2019

 

 
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DAY 1

- 8/6/2018