https://www.yiweichanglab.org/research daily 1.0 2024-06-01 https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/1534385627351-WXSCES7O6XIRXM7PXO4R/cryo-ET_3_wide.png Research interests https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/1534434467969-XQVWT255MXJFAWZM564L/cryo-ET_2.png Research interests https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/1534437028728-1ZK5PV5UITYQZIYEVQSL/Hs746T_pylori_20130415_78.png Research interests https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/1534440727334-PUSZBF3IA8ARR9H6MG0N/20180619_piliated_12_with_pilin_and_wider_membranes_and_PG.png Research interests https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/1534444070319-O2ALLQP9YEOD7AGXGARM/Poster_48x48.jpg Research interests https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/1639540508681-BDESWQBAGAM48X6BLEFT/Apicomplexan_RSA2.jpg Research interests https://www.yiweichanglab.org/team daily 0.75 2026-01-16 https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/1631328741068-FZA1C9UKXE68Z06P1JSV/Yiwei2021.jpg Team - Yi-Wei Chang Principal Investigator (Penn page) https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/3ed151cb-cc2d-4a38-9788-d75bfe0574c3/WaiCheung3.jpg Team - Yee Wai Cheung Postdoctoral Scholar https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/249f87a3-44d7-4e1a-8af8-422a10528ef5/Tingting_Chung.jpg Team - Tingting Chung Undergraduate Student https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/1549501956058-XIHZLYTWIZS493H0BUCL/Longsheng+Lai Team - Longsheng Lai Postdoctoral Scholar https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/1badea24-13ad-4c89-b536-09440fdc12a1/Jasmine_2025_4.jpg Team - Jasmine Larrick MD/PhD student https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/eeea913f-7fcf-4993-a583-8af18f89cf87/Fenglin_Li.jpg Team - Fenglin Li PhD Student https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/5e273b07-f91b-4ef8-ae75-724e6b813ea1/Lucas2024.jpg Team - Lucas Morley PhD Student https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/6a5aa559-9b03-4125-99c5-a04cc9ce9539/Quynh2024.jpg Team - Quynh Nguyen PhD Student https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/f65af264-b926-41a2-b815-62162072a89d/Ijeoma.jpg Team - Ijeoma Okoye PhD Student https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/82aed89b-52ab-43c7-8734-61f21ebf28d2/Sharon.jpg Team - Sharon Patray Postdoctoral Scholar https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/68f771c4-ca17-4cb3-8e55-954b43d2fff8/Niharika_2024.jpg Team - Niharika Shukla MD/PhD student https://www.yiweichanglab.org/publications daily 0.75 2026-02-16 https://www.yiweichanglab.org/labphotos daily 0.75 2026-03-06 https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/d6711c25-135f-4634-b855-62a261a23c47/Yi-WeiChang_tenure_party.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/7a4e9cc9-1dc6-483e-bee4-b0e38fec154e/BenCreekmore_Yi-WeiChangLab.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/ccdc717a-fb7f-4285-af54-df302cb867df/Yi-WeiChangLab.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/eee17a4d-5241-45e7-9a14-88aff4d1d9e0/KatieKixmoeller_Yi-WeiChangLab.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/be2a2cb3-8e74-43c7-953b-28f813379a8e/IMG_3704.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/b7c59b23-4a89-4ac5-a6dd-5df41083a3d7/IMG_3704_1.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/50e8cd2d-13b5-4075-9a62-7980c9bf7701/Yi-WeiChangLab_2025_BBCB_retreat.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/f7d4df4e-35e1-4159-98d2-533c97b04597/IMG_3211.jpeg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/635d1ddf-a1f4-4d3a-9a63-976f83975ca7/IMG_3211_crop.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/4b17c0ea-253e-4247-a431-4d24a3d36610/Tingting_Chung.jpg Lab news and photos - Tingting received the College Alumni Society Board of Managers and Presidents Undergraduate Research Grant! - 11/26/2025 https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/980e88b1-de3c-4821-a2c7-9b0e1d38559c/LeonDefenseFlyer.png Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/0516cf53-4102-4009-92f2-f2d9e3ad64bb/IMG_3085_crop.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/09001ce0-1e08-4898-b799-e5f4c753d4b1/IMG_3011_cropped.jpeg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/11905ca0-1de6-465e-bfb3-9b346baa0b7c/IMG_3059_cropped.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/9a971456-1574-4b98-8807-78757fbf283d/PennCSO_post.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/9443322b-83ed-49af-aa08-5ce4da0f1e24/2025_Ruchao_Xin.jpg Lab news and photos - Ruchao and Xin received the annual S. Walter Englander Award for Postdoctoral Research at Penn!! For their exciting work on the Flu RNP structure and mechanism and the demonstration of the power of collaboration to make transformative discoveries. -10/22/2025 https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/68f771c4-ca17-4cb3-8e55-954b43d2fff8/Niharika_2024.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/5e273b07-f91b-4ef8-ae75-724e6b813ea1/Lucas2024.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/4b17c0ea-253e-4247-a431-4d24a3d36610/Tingting_Chung.jpg Lab news and photos - Tingting received the Mary L. and Matthew S. Santirocco College Alumni Society Undergraduate Research Grant! - 6/2/2025 https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/55933ef3-c49f-4653-a23a-48e369c8941c/PengRuchao_influenza_RNP_complex.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/8d46fd76-9811-4159-a5d6-d9ee38758ef8/cryo-ET+of+kinetochore Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/44fddf85-0312-4fc3-9619-805e65d481d2/Screenshot+2025-01-23+at+8.19.12%E2%80%AFPM.png Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/ead4e2c1-d62a-4b86-a6f2-ca27d2eb80f5/IMG_9964.jpg Lab news and photos - Leon won the Ruth Keris Award for Departmental Service! This annual award recognizes Leon’s above-and-beyond service and leadership in the community of the Department of Biochemistry & Biophysics and the BBCB graduate group. - 12/6/2024 https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/92089004-5ace-4ef6-9f48-1c140a690c32/IMG_6561.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/a474ef0d-bac7-4aba-85e4-d3aa20af84cf/Changlab_2024May.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/1613743791778-MIBLX8B720YX2UKGGO4V/Katie4.jpg Lab news and photos - Katie won 2024 Saul Winegrad Award for Outstanding Dissertation! The Award was established in 1995 in honor of the founding Director of Biomedical Graduate Study at Penn, Saul Winegrad, MD, Emeritus Professor of Physiology. The award was created to recognize a dissertation of outstanding quality which makes a significant contribution to biomedical science. - 4/25/2024 https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/a3c197cf-48ea-45b4-b4b3-f5f4ef310b11/Matt+Martinez+Thesis+Defense+Flyer.png Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/4799fcd3-f0b0-4b5f-9fb2-7f0631701ab1/IMG_6169.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/1869527a-c46f-47f6-a268-3ddb3660102c/IMG_6144.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/33b97bca-2e3d-42d4-9a9b-101c9c7ddc8e/IMG_6188.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/97454799-27fa-4ead-9761-1143763da67a/cryo-PFIB-ET_human_brain.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/90342279-e34e-4cf8-8d71-e23dc3006545/Katie+Kixmoeller+Thesis+Defense+Flyer.png Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/dd3c0dd3-b96e-4bc4-9c79-0372d9b91310/IMG_5906.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/5d5c970c-354b-4773-b5b1-618064d08a60/IMG_5900.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/3326a2cc-3936-4b89-856b-c5552e0f4012/IMG_5914.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/5625e0ce-3037-486c-8d49-473378e37afc/Benjamin+Creekmore+Thesis+Defense+Flyer.png Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/764a4861-8f04-4fa3-9820-dd704ca4b32c/IMG_5845.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/f25e2378-b08e-4036-a3ee-e14de7d7a488/IMG_5859.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/49d68b09-592f-4dc1-bdc0-ca61a97b3d4a/IMG_5855.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/90955f48-788f-47ab-8547-341a292b6080/2024_NatureComm_Editors_highlight.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/1613743791778-MIBLX8B720YX2UKGGO4V/Katie4.jpg Lab news and photos - Katie won John G. Clark Prize! 2024 Medical Student Research Paper Prize Competition Title: Visualization of human kinetochores by cryo-electron tomography 3/15/2024 https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/1626454899608-YONJNW05VUEB14779NSY/Ben.jpg Lab news and photos - Ben won Neurosurgery Research Prize! 2024 Medical Student Research Paper Prize Competition Title: Ultrastructure of human brain tissue vitrified directly from autopsy revealed by cryo-electron tomography with cryo-plasma focused ion beam milling 3/15/2024 https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/7654abc1-c767-4098-9a63-0198e57c67b1/2023_Yi-Wei_Chang_lab_BMB_retreat.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/e8df8c49-e72d-43c1-a1f9-6bf4925bd326/Mildred+Cohn+Postdoc+Award+Congratulations+Flyer+51923+%282%29.png Lab news and photos - Ruchao received the Mildred Cohn Distinguished Postdoctoral Award! - 9/1/2023 https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/5fb17413-ed04-42fc-bd65-3fadd00854b1/Matt_2022_2.jpg Lab news and photos - Matt received the Blavatnik Family Fellowship in Biomedical Research! - 9/1/2023 https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/21caeed9-b678-442d-a02b-239f32450800/2023_F-actin.png Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/2b3a6ea6-23cb-4eeb-8a3a-83c63e3293f8/ISB_Yi-Wei_Associated_Director.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/fff58c11-e207-47a7-a231-ec178ce51713/twitter_FwgbM9FaYAI3dVI.jpg Lab news and photos - Yi-Wei named Burroughs Wellcome Investigator in the Pathogenesis of Infectious Disease - 5/19/2023 https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/1631329185427-FJ6DX49WQYF4M7P1W3UU/Leon2021.jpg Lab news and photos - Leon won NIH F31 fellowship!! - 3/30/2023 https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/1621e47d-c8f4-435b-bc04-98527dd3c8a6/2023_Leon_MolecularCell_paper.png Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/85f1bde6-1def-4888-8740-fe9f08ac685a/IMG_7740_.jpg Lab news and photos - Matt won the 2022 P. Leslie Dutton Award for Outstanding Publication by a BMB student! and delivered a wonderful award presentation at the BMB annual retreat! - 2022/12/2 https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/72d8fbd9-2f11-4dc4-bb2c-9ffdc4a1d753/Matt_talking_at_MPM2022.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/1626454899608-YONJNW05VUEB14779NSY/Ben.jpg Lab news and photos - Ben won NIH F30 dual-degree fellowship!! - 8/19/2022 https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/1589565846118-DFJ3492LYG2XDU52N5Z5/Liam+Theveny Lab news and photos - Liam is joining Harvard for his PhD! Congratulations to our long-term, super-productive undergraduate student Liam Theveny! We can’t wait to see all the amazing things Liam will be doing at Harvard! - Summer 2022 https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/1549502088333-5MRET5Z9LKDWYFLGLBW6/IMG_7342.jpg Lab news and photos - Billy is going to Caltech for his PhD! Congratulations to our inaugural lab member William (Billy) Chen! After spending the entire undergraduate time in our lab and made countless contributions, Billy is going to Caltech and blow everyone there away! - Summer 2022 https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/ff6ead97-d4ae-43ed-aba9-849502639603/IMG_6658.JPG Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/edbd986e-1b63-4695-b7d4-72987f6a2658/IMG_6650.JPG Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/72940d19-c5b7-4e15-83fd-e436bc99b3eb/2022_Plasmodium_RSA_NatureMicrobiology.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/888766b8-b215-4034-ab97-baf3b29ecef1/IMG_5711_new.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/fbde2d33-33ec-40ef-9ecd-4b4a4fb142db/TIPcover2022.tif.jpg Lab news and photos - We are on the journal cover! https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/9cd677a1-51d7-4559-b730-407a375a5eb3/embj.v41.5.cover.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/5fb17413-ed04-42fc-bd65-3fadd00854b1/Matt_2022_2.jpg Lab news and photos - Matt won the inaugural Martin and Pamela Winter Infectious Disease Fellowship!! - 02/24/2022 https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/96f210c0-1329-4d75-a70b-3aca47ef0e6b/TrendsinParasitology_2022_2.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/bb87601b-45ad-4d92-8ae0-d001887221a5/2021SecretSanta.jpg Lab news and photos - Secret Santa 2021 - 12/16/2021 https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/0d519964-2e28-4c8e-98d3-c6e7b459c158/twitter_FF9bVNCXsAcnhQ3.jpg Lab news and photos - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5b74baf7b98a78e0dc642614/4804cd13-5930-474b-a6e3-51fa1ce56d27/Shrawan.jpg Lab news and photos - Shrawan won the annual S. 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